There is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects. Nanomedicine in Drug Delivery gives an overview of aspects of nanomedicine to help readers design and develop novel drug delivery systems and devices that build on nanoscale technologies. Featuring contributions by leading researchers from around the world, the book examines:

The integration of nanoparticles with therapeutic agents
The synthesis and characterization of nanoencapsulated drug particles
Targeted pulmonary nanomedicine delivery using inhalation aerosols
The use of biological systems—bacteria, cells, viruses, and virus-like particles—as carriers to deliver nanoparticles
Nanodermatology and the role of nanotechnology in the diagnosis and treatment of skin disease
Nanoparticles for the delivery of small molecules, such as for gene and vaccine delivery
The use of nanotechnologies to modulate and modify wound healing
Nanoparticles in bioimaging, including magnetic resonance, computed tomography, and molecular imaging
Nanoparticles to enhance the efficiency of existing anticancer drugs
The development of nanoparticle formulations
Nanoparticles for ocular drug delivery
Nanoparticle toxicity, including routes of exposure and mechanisms of toxicity
The use of animal and cellular models in nanoparticles safety studies

With its practical focus on the design, synthesis, and application of nanomedicine in drug delivery, this book is a valuable resource for clinical researchers and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner. It explores a wide range of promising approaches for the diagnosis and treatment of diseases using cutting-edge nanotechnologies.


Table of Contents

Nanoparticles in Drug Delivery Systems
Emilio Castro and Arun Kumar

Synthesis and Characterization of Nanoencapsulated Drugs
Arun Kumar, Ashley E. Saienni, and Niketa Dixit

Nanoparticle Lung Delivery and Inhalation Aerosols for Targeted Pulmonary Nanomedicine
Heidi M. Mansour, Chun-Woong Park, and Don Hayes, Jr.

Biological Systems for the Delivery of Nanoparticles
Niketa Dixit, Mark Glaum, Arun Kumar, and Don F. Cameron

Nanodermatology: The Giant Role of Nanotechnology in Diagnosis and Treatment of Skin Disease
Adam Friedman

Nanoparticles for Drug Delivery of Small Molecules
Ana Sofia Macedo and Eliana B. Souto

Nanoparticle Therapies for Wounds and Ulcer Healing
Chiara Gardin, Letizia Ferroni, Luca Lancerotto, Vincenzo Vindigni, Chiara Rigo, Marco Roman, Warren R. L. Cairns, and Barbara Zavan

Nanoparticles in Bioimaging
Javier L. Pou Ucha

Nanoparticles in Anticancer Drug Delivery
Frederic Lagarce

Formulations of Nanoparticles in Drug Delivery
Sushama Talegaonkar, Mohammad Tariq, and Zeenat Iqbal

Nanoparticles for Ocular Drug Delivery
Jaleh Barar and Yadollah Omidi

Toxicology of Nanoparticles
Siva K. Nalabotu and Eric R. Blough

Animal and Cellular Models for Use in Nanoparticles Safety Study
Kevin M. Rice and Eric R. Blough

Index